Clone CD or CDR Win

In my opinion you need both. Games that don't need patching are best copied with CloneCD. For best results ensure that your burner can handle DAO+96 RAW mode; the Elaborate Bytes site lists compatible burners and what they handle.

CDRWin is necessary when you have to patch a game. Usually that is to defeat copy protection or to patch the game to work with a particular pboot method.

Your burner needs, of course to be compatible with both programs.