For a v5 it shouldn't be a problem. Make sure your boot disc has a larger TOC than the game you are booting. You can not use CloneCD for dvds. CloneCD only supports cdr. They are working on a CloneDVD program. For cd based PS2 games(blue backs) use CloneCD, for dvd games use RecordNow Max or PrimoDVD. Nero also works but it can have some problems with some games. You can read the tutorials for the above programs
here