Do DVD games need to be patched?

[arcane]

The reason that I ask is because in the past I have always had to patch any images that I burned from CD based games onto CDr. They wouldn't work otherwise (or they would half work i.e. load the title screen and then freeze when entering another mode of the game). Has anyone burned a game to a DVD+r and then ran it on a non-modded PS2 using the GameShark?
Thanks again