geez, Win2k Pro is the most stable Windoze operating system out there (I have not tried WinXP yet).
I run CloneCD with no problems in Win2k Pro SP1 or SP2. I would uninstall CloneCD, use the program to clean out the CloneCD registry settings, defrag then reinstall the latest version of CloneCD.
Like I said, mine is solid as a rock and the only reason I ever go to WinME (I have a dual boot system) is to play games. All my other work is done in Win2k Pro