With your Plex24X you will never have to use AWS (well I can't see into the future, but so far you shouldn't use it). Hide CD-R Media - this is needed on most new games if you play them in your writer. If you play them in a standard CD-ROM you won't need it (only cd-writers mainly can read the ATIP on a CD - which if found to be present the game run)
The ATIP is a small section on every CD-R that holds the manufacturers name, length etc. This ATIP isn't present on pressed Cd's, so if there is ATIP present then it won't play. When Hide CD-R Media is enabled, it hides that the game is burned, and so you will be able to play it.
You can download Clony XXL at
http://insomnia.covers.de/ use the settings it gives you for each protection.
When it comes to SD2.51.021 on the Plex: Read the game to an image file at no more than 4X, patch with the NEW Betablocker, burn at no more than 6X. And use Hide CD-R Media if playing from a burner.