Yep realize its not an easy task.
Instead of trying to stop the hackers would there be a way of spotting the hackers.
In other words, let the hackers into the game but have a program which allows the server gameops to spot those people using the hacks.
This would be just as effective providing there are gameops about to watch the game.
These are just thoughts btw. My theory is let an idea loose and there is the possibility someone will turn the idea into a reality.
I am putting the idea out there to get peoples thoughts on it.
I do think it is a lost cause, but you dont know until you ask.