i got 1.15 to work perfectly with help from post #240 and others
1) install game
2) update to 1.15
3) right-click titanquest.exe and change to win2000 compatability
4) mount "Titan Quest [ENGLISH] No-DVD/Fixed Image #2" from gamecopyworld with daemon tools (all emulations off)
5) run alkisecurom.exe (
download it) and double-click titanquest.exe
i didnt need Pr0t.St0p, but it has helped others...