Referring to casio's post several pages earlier :
must have CureRom installer, DaemonTool installer, Bender's mini-image for TQ (look for it at gamecopyworld and store it at a permanent place u want coz we'll use it everytime we want to play), Titan Quest the game itself, and the patch (try to look for it at the titanquest official website, coz i got mine from fren) ...
1. Uninstall the game
2. Uninstall CureRom and Daemon tool
3. Restart pc (coz, u must, if u try, u'll see)
4. Install the game
5. Patch the game
6. Install Daemon tool
7. Install CureRom - create new profile -> click Next -> For application, browse for ori titanquest.exe file from where-u-install-it -> click Next -> Image mounting software - use Daemon tool -> Backup file - choose the mini image u download earlier -> click next -> Put the shortcut name (whatever u want) - >click Next -> Click Save -> Click Finish
8. Double click the Icon that u just created (with the name that u wrote before).
9. See if u can play
From my experience, while installing the game, it's like there is some kind of Daemon tool, or Cure Rom detector that was executed during installation, so, thats why i dunt need those software before installing the game.
Good luck
edit : need to download the patch oso
edit 2 : u can also try to use maciozo's mini-image, also, can get at the same place.