Starcraft 2 is in the works...
(
http://www.starcraft2.com/ according to rumors indicates that Blizz is working on SC2 for almost 4 years now.. )
As for Duke Nukem Forever do i need to comment ? Its in the works for more than 6 years now...When it was first announced the graphics were spectacular, now they are just LOW....If they plan to change the engine every 3 months to keep up with the new GPUs they will never release it.