Well the way I did it was pretty simple and it worked so there's nooo reason why it shouldn't work for any1 else as well.
I guess i'll give u all the detailed step by step version so any1 can follow and accomplish it
First install Madden 2006 like you normally would
second thing...is make an image file of the first cd (i used the original)...I used Games X Copy for this...which is absolutely flawless software...besides Halflife2 there is no game that this software was not able to copy or image.
Then go download Daemon tools 3.47 (is what i used)
http://cdmediaworld.com/hardware/cdrom/cd_utils_8.shtml
if link doesn't work put "daemon tools 3.47" into google and find it that way
install it and it will create a virtual drive on your computer (doesn't matter if you don't understand what a virtual drive is...u will see an additional letter in your computer directory)...launch daemon tools and it will ask you to load the image file...go to where you created Madden 2006 disk #1 image file and load it. For games x copy images you have to change dameon tools' search to "all files" then you will be able to see the image files. Load disk #1 into daemon tools...now go run Madden 2006 via the shortcut on your desktop (or wherever u have it) and you are running.
Enjoy !