[The One]

Putting the CDs into different folders with an autorun probably wouldn't work for most games unless they are cracked and don't require any data from the disc during gameplay. Also during install you'll keep getting a prompt for the next CD and you'll have to select the folder. Most games will put the install source path somewhere and be something like E:\Setup. If you put the CDs in seperate folders, the game will look for the game in say, E:\CD1 but the 4th CD is in E:\CD4. If you are putting different games all on one DVD but all files from each games CDs are in this folder it will probably work except in rare cases where the setup must be run from the root of the drive which I have ran across before. The game may also need to be crack even if there is no protection because some games will only look for the game files on the root of the install drive.

These are the games that I have coverted to DVD
Baldurs Gate 1
Hitman Contracts
Painkiller
FarCry
KOTOR
Enter the Matrix
Commandos 3
LOTR ROTK
UT 2k4
Splinter Cell

And maybe some others that I don't remember

I'm looking at Emperor Battle for Dune and it looks like it cannot be converted to 1 DVD because the movie files from each CD have the same names. This means they will overwrite each other and I'm sure there is no way to change the path that the game looks for the movies. I'm sure it just looks for the movies in the setup source path.