This is how it works.
Problebly the SafeDisc 2.8 as operation Flashpoint are, has been chashed in you ram when you put in you original CD.
And did a copy and maybe install the game.
So when you restart you computer and turn it off, Windows Clears the cash (as logical) and you SafeDisc aren't buffering. (observer is only Safedisc for Operation Flashpoin: GOTY that I talking about. Other games also cash in the memory but you might not have run another game then Operation Flashpoint becuase if you did and try to run OFP again you might see the backup copy don't work ether..

)
You can dump your CD to harddrive and mount the image in Alcohol-Software..
What software did you use to make a backup?