I started out with that same combo except on a V4. I used DMC as my first swap and it worked fine....for a while. Then all of a sudden I couldn't boot DVD-R anymore. I almost spent a lot of money to replace the laser. Instead I thought I would try a set of Swap Magic disc's that my friend had. They booted every game I have no problems. I know there are some issues on them booting RIPS and some large TOC games but I have not had a problem booting all including GTA Vice City. I don't even use the NEO Key at all. You will hear mixed reactions on these disc's. All I know is that it solved my problem. If you are looking for a cheap possible solution it might be worth a try. If you got the money, get a Messiah 2 installed. Hope that helps.