G'day Sixx2,
Some of my backups only play from my DVD Drive & not the CDRW as you said. I wouldnt say the DVD drive is the issue here.....
Unfortunatley, I dont have the benefit of having Unreal 2 yet as we "Down the Land Of AUS" take a whiles to get games.......
If you have CloneCD installed..... right click the Sys. Tray Icon & ensure Hide CDR Media is ticked...... (It's simply hiding the fact that the Backup Copy is a CDR disc)
Then start the game again in your DVD drive & see if that works........ in some cases this works for me........