Venom: Codename Outbreak
 

I just picked up the full version, but it's protected using a new version of Laserlock apparently. I need a No-CD Needed .exe file replacement for the main file to play in single player mode, and to server multiplayer games. However, interestingly enough, you can change the file name of outbreak.dll to outbreak_lan.exe and play in multiplayer mode.

If you haven't heard of the game yet, check it out at:
http://www.venom3d.com/fs_news.html