So I should buy a second sound card and try it. I got a Audigy 2 ZS in my FX workstation.

Postal, if the game doesn't work with an Audigy 2, then I guess the soundcard isn't the reason. Before you get a new one, try setting the hardware acceleration to minimum (Run dxdiag, rider "sound").
If the game still crashes, it's unlikely that your Audigy is responsible.

The audigy 2 isn't in this comp. Its in my workstation comp which is nice and beefy for maya 6 rendering.

A couple of my friends had the game crashing or not even starting because they had a joystick connected, not sure if that will help anyone but it's nice to know.

i got the same problem :(

A bunch of my friends and I could not get the game to start. For some reason, reinstalling the game fixed it for all of us.

I have an audigy 2 value and the game runs ok

i reinstalled it few times, still wont run

with my Audihy2 ZS everythink is working 100% fine..no Probs so far!

latest Drivers ?

I'm buying another audigy 2 zs. I can spend the 50 bucks as the game costs 55 :)

GTA got Problem with Alcohol virtual drive
 

The Game doesn't start with Alcohol Virtual Devices. Turn them off. I use the official crack and got the german Retail version of gta (no download version) and it works fine with Leadtek 6800 GT AMD 3000+ 1024 MB Ram, Thrustmaster Joypad, onboard sound

I have Audigy 2 and I get lock ups all the time...

I have an Audigy 2 Platnium and I have no problems?

I have onboard sound & haven't had a single problem yet with the crack or with anything else. It's all run just as it should :)

I think I now whats the problem:

As you may know HOODLUM is a WAREZ Release-Group. They are releasing complete games not only cracks. The crack you can find on GCW is just ripped out of the HOODLUM Release. But the HOODLUM Release is an US-Version so the crack is also for the US Version (which of course only supports English and Spanish).

I think those wo have problems with the crack have got the EU Version (with German, French, Italian, English, Spanish language support) or the german version (the same as the EU Version but cutted). So its not a broken crack. The crack is simply incompatible with your version.