/Boring ;)

You're doing nothing special, & neither is your reg change. All you're doing is the standard full image procedure.
The reg change is also highly likely to bork up things elsewhere.

-Leezer-

Yeah I know I'm doing nothing special, but if I don't change the reg key, my system won't boot (BSOD and stuck at Windows startup logo).

I have a possible solution, please check if you can get it to work. It worked on both my notebook and my desktop:

0. Install Daemon Tools 4.0.3 and CureROM 2.0.3.
1. Mount the image of the Game using Daemon Tools (Mds ISO etc).
2. Open CureROM - Options (Bottom Right) - CureRom Settings
3. At the Third Party Virtual CD/DVD-ROM section, Make sure Daemon Tools is chosen and the "Do NOT display "DAEMON Tools" in my Virtual CD/DVD-ROM list." check is selected. Click Apply and Close.
4. Create a New CureROM profile - Choose Application by browsing EXE file of The Game. Make sure the "CureROM AntiBlacklist Measures" check is selected.
5. Click: Next, Next, Put in a Good Shortcut Name.
6. Next, Save, Finish.
7. IMPORTANT: Make sure Daemon Tools is NOT running (If there's the Daemon icon on the right bottom icon, right click and then Exit). Do not Unmount the images.
8. Run the Shortcut.

Works for FM 2006 6.0.0 and Patched version 6.0.3.

Let me know if that works for you guys.

EDIT: I have problems setting it using the --windowed, I put that into CureROM setting and it still wouldn't work.

I'd try it...it works well only 2 times, after than my system won't boot.
I think it's the 6.0.3 patch...maybe it has a special securom/safedisc engine...or maybe game's safedisc engine conflict with a windows xp hotfix ?

Its working fine here, I had to make sure my Firewall doesn't crash CureROM, because it was like that the first time. Did u try to re-install and see if that works with 6.0.0?

My troubles is when playing network games, you have to exit almost all (in my case, all of them) of the protection software that I have, ZoneAlarm and Norton Antivirus. Darn it ...

You should get rid of Symantec/Norton Antivirus anyway because it's known to have too many false negatives and positives! :(

Hmm, I often read messages bagging Nortons programs, I have used Nortons SystemWorks for many years now, never had a virus, never had false postives, never had false negatives.
Yes it may be heavy on the resources at times but I really dont have a problem with that.
I dont use game trainers so I dont get false negatives there.

And sometimes out of curiousity I check suspect files with the online virus scanners and they dont tell me anything that Nortons does or doesnt.

So I do believe people who do have problems with Nortons either dont have it configured correctly or are using a warez copy of the program.

Now I still use Norton SystemWorks 2004 and Nortons Ghost, they are the only 2 Norton programs I use and I am more than happy with them both. ;)

But everyone to the own I guess. :)

For those who're having problems using my guide, like not working when it worked before, try restarting. If that doesn't help, reapply the Daemon image (don't forget to exit the program afterwards) and reapply the CureROM profile you made. It helped me. :)